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Dechallenge and Rechallenge in Drug Side Effects: What These Tests Mean

Dechallenge and Rechallenge in Drug Side Effects: What These Tests Mean

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Dechallenge and Rechallenge in Drug Side Effects: What These Tests Mean
  • By Percival Harrington
  • /
  • 3 Jan 2026

Dechallenge and Rechallenge in Drug Side Effects: What These Tests Mean

Dechallenge and rechallenge are key methods used to confirm if a drug is causing side effects. Stopping the drug to see if symptoms improve is dechallenge; restarting it to see if the reaction returns is rechallenge. These steps help doctors and regulators determine true drug-caused reactions.

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